Type of Drug:Male hormones.
How the Drug Works:
lostosterone is the primary natural androgen (male sex hormone) produced by the testes. Androgens promote normal growth and development of male sex organs (eg, prostate, seminal vesicles, penis, scrotum) and affect fertility. They also produce the distinctive male characterisis of hair distribution, voice depth,
Uses:
To treat testosterone deficiency. Prolonged treatment is required to maintain male sex characteristics.
For hormone deficiency due to developmental defects of the testes. To treat delayed male puberty (brief treatment with low doses) in carefully selected patients. To treat male impotence caused by androgen deficiency (methyl testosterone only).
Used for breast pain and swelling in women immediately after childbirth. Also used as secondary therapy in postmenopausal women for advanced, inoperable breast cancer that has spread to other areas, including bone.
Unlabeled Uses: Testosterone tenantable has been studied for male contraception.
Precautions:
Males frequently experience breast swelling or development. Reduced sperm counts may occur after prolonged use.
Women may show signs of masculinization: Deepening of voice, hair growth, acne, increased size of clitoris, menstrual changes. These symptoms usually follow high doses of androgens and should be tolerated during treatment for advanced breast cancer. Treatment may have to be discontinued. Consult your doctor. (The trans dermal systems have not been tested in women and should not be used by women.)
Product interchange: Do not try to substitute short-acting and long-acting testosterone products. These products are not considered to be interAchangeable.
Athletic performance/physical appearance: Anrlrooens are not safe and effective for enhancement of athletic peroformance or physical appofunee; usa could produce serious adverse effects.
Fluid retention: Since androgens may cause fluid retention, use with caution in epilepsy, migraine, and heart, liver or kidney disease.
Pregnancy: Do not use during pregnancy. The risk of use in a pregnant woman clearly outweighs any possible benefit. Androgens may masculinize a female fetus.
Breastfeeding: It is not known if androgens appear in breast milk. Consult your doctor before you begin breastfeeding.
Children: Androderm has not been tested in males under 15 years of age. Has not been tested in males under 18 years of age. Use other androgens very cautiously in children under 18 years of age. Androgens may stop or stunt the growth process.
Elderly: Use with caution in elderly males. Androgens may increase risk of prostate enlargement or prostate cancer. An increase in sex drive may occur.
Lab tests may be required to monitor therapy. Be sure to keep appointments.
Tartrazine: Some of these products may contain the dye tartrazine (FD&C Yellow No.5) which can cause allergic reactions in certain individuals. Check package label when available or consult your doctor or pharmacist.
Drug Interactions:
Tell your doctor or pharmacist if you are taking or if you are planning to take any over-the-counter or prescription medications or dietary supplements while taking this medicine. Doses of one or both drugs may need to be modified or a different drug may need to be prescribed.The following drugs and drug classes interact with this medicine.
Side Effects:
Every drug is capable of producing side effects. Many patients experience no, or minor, side effects. The frequency an severity of side effects depend on many factors including dose, duration of therapy and individual susceptibility. Possible side effects include:
Female -Irregular menstruation; absence of menstruation; deepening voice; enlargement of clitoris; changes in sex drive.
Male - Breast tenderness, swelling or development; decreased sperm count; erection problems (pain, frequency, increased duration); changes In sox drive; itching, blisters, bruising, hardening, redness, discomfort or Irritation (patch only); enlargement of the prostate.
Nervous System: Hoadache; anxiety; depression; sleep disorders; memory lodd;abnormal skin Ronsations.
Skin: Excessive growth of body hair; loss of scalp hair; acne; oily skin; changes in skin color (yellowing); rash; irritation (patch only).
Other: Fluid retention (edema); ankle swelling; nausea; pain at injection or implantation site; increased cholesterol; liver problems; vomiting; dilated pupils; abnormal bleeding or bruising; inflammation of the mouth (tablets only); stroke; black or tarry stools; urinary tract infection.
Guidelines for Use:
Oral tablets - May cause stomach upset.
Buccal tablets - Do not swallow. Allow to dissolve between the gum and cheek. Avoid eating, drinking or smoking while tablet is in place.
Notify your doctor if nausea, vomiting, swelling of the extremities (edema), prolonged or painful erections, or yellowing of the skin or eyes occurs.
Female patients - Notify your doctor if hoarseness, deepening of the voice, hair growth changes, acne, menstrual irregularities or suspected pregnancy occur.
Androgens are not effective and may be dangerous if used for fractures, surgery, convalescence, bleeding of the uterus or enhancement of athletic performance or physical appearance.
Brand interchange - Do not change from one brand of these drugs to another without consulting your pharmacist or doctor.
Testoslerone injections - Shake well before using. Administer into buttock muscle only. Effects of enanthate and cypionate injections last about 4 weeks.
Transdermal systems - Read patient instructions. Store at room temAperature (59A°-86A° F) in provided pouch until ready to use. Carefully disAcard used patches to prevent accidental application or ingestion by others (eg, children, pets).Androderm: Place on clean dry non-scrotal skin (eg, back, abdomen, upper arm, thigh) every night. Rotate application sites, allowing 7 days between applications to the same site. Site should not be oily, damaged orirritated. Patch does not need to be removed during sexual inter- course or while bathing. Testoderm: Place on clean, dry scrotal skin. Scrotal hair should be dryAshaved lor best contact. Do not use depilatories (chemical hair removAers). System should be worn 22-24 hours, but can be removed for swimming or bathing and then reapplied. Lab tests should be made after 3 to 4 weeks of use.
Pellet implantation - Report any unusual irritation or infection at the implant site. If treatment is discontinued, the pellets will have to be removed.
Femalesexual partners of male testosterone patients should contact a doctor the following occur: changes in body hair distribution or increased acne.
Do not alter the dose unless directed by your doctor.
Diabetics may require insulin dose adjustments. Consult your doctor.
Lab tests or exams may be necessary. Be sure to keep appointments.
Store tablets in a closed container at room temperature.
Avoid freezing inject able products.
No comments:
Post a Comment